The aim of these studies is to investigate why there are differences in treatment effects in patients with migraine and which research designs that are most effective in assessing these treatment effects. The studies include investigation of both acute and chronic migraine treatment. 

The studies are funded by the Lundbeck Fonden, the Aarhus Universitets Forskningsfond and the Helsefonden. 

20% of the Danish population suffers from chronic pain, which has extensive consequences for patients' quality of life. Chronic pain is both complex and can be challenging to treat with medication. One type of non-pharmacological treatment used for chronic pain is spinal cord stimulation. By implanting electrodes in the spinal cord, this treatment utilizes electrical impulses to stimulate nerves, potentially alleviating chronic pain for some patients. Currently, research and testing of the treatment are primarily funded by the industry, including manufacturers of stimulation devices. The latest independent research in the field indicates significant uncertainty about the actual effectiveness and mechanisms of the treatment. However, research may not necessarily reflect the treatment's effectiveness in clinical practice. For the first time, this study examines the impact of spinal cord stimulation using a new well-controlled and clinically relevant research method. The research design specifically investigates the pain-relieving effects of spinal cord stimulation when isolated from other environmental factors, such as expectations. The study particularly focuses on ensuring the investigation is representative in clinical practice and therefore examines the patients receiving the treatment. The project allows for a precise understanding of treatment effectiveness, ensuring that the treatment is not administered unnecessarily and is given with the best possible outcome for patients.

The studie is funded by the Danmarks Frie Forskningsfond

This study examines how pain is experienced and processed in patients with Parkinson's Disease.

The study is funded by the Danmarks Frie Forskningsfond

Project involving, among others, Lene Vase and Asger Reinstrup Bihlet.

The study of funded by the Innovationsfonden.

The purpose of EDULOX is to investigate the effectiveness of two different treatments: patient education and medical treatment, either alone or in combination, for patients with severe functional disorder. Severe functional disorder (multiorgan BDS) is a condition characterized by numerous persistent and disabling symptoms. The disorder results in reduced quality of life and lost work capacity, imposing significant costs on society in terms of increased expenses in the social and healthcare sectors. It is estimated that at least 1% of the Danish population suffers from multiorgan BDS.

In recent years, treatment options for multiorgan BDS have improved with increased research activity and the establishment of several treatment centers in Denmark. However, treatment options supported by research are still limited. Clinical trials have shown the effectiveness of certain types of psychological and medical treatment, but these treatments require highly specialized therapists or are only suitable for selected patients. There is therefore still a significant unmet treatment need. Primarily, there is a need for knowledge about treatment modalities that can be delivered by less specialized professionals to a broader patient group.

The project is funded by the TrygFonden.

Animal-Assisted Therapy (AAT) is growing and has the potential to become an important non-pharmacological supplement for the treatment of individuals with conditions such as mental illness, stress, or developmental disorders. Research indicates that the use of animals in therapeutic treatment can have significant effects on various target groups, but it is not clear what specifically about the contact with animals influences the treatment outcome. The project is divided into four work packages, where the first phase involves identifying and selecting physiological, psychological, and various behavioral measures for the effects of different degrees of contact with animals. In the latter half of the project, we investigate the immediate reactions of nursing home residents and military veterans to contact and interaction with dogs using the selected measures.

The project is funded by the TrygFonden.